Saguna Verma

Junior Researcher

Retrovirology Research Laboratory

Atherton Building, Leahi Hospital, Second Floor

3675 Kilauea Avenue, Honolulu, Hawaii 96816

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email: saguna@hawaii.edu

   

 

INSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDY
Devi Ahilya University, Indore, India B.S. 1985 Zoology, Chemistry, Botany
Devi Ahilya University, Indore, India M.S. 1987 Biochemistry
Devi Ahilya University, Indore, India Ph.D. 1994 Biochemistry
 
Professional Experience
1989-1991 Junior Research Fellow, School of Life Sciences, Indore, India
1992-1993

Senior Research Fellow, School of Life Sciences, Indore, India

1994-1999 Project Scientist, Genes and Proteins Laboratory, National Institute of Immunology, New Delhi, India
2000-2001 Guest Lecturer, Vaid's Institute, New Delhi, India
2003-Present Junior Researcher, Retrovirology Research Laboratory, Pacific Biomedical Research Center, University of Hawaii, Honolulu, Hawaii

 

Honors and Awards

1985 Merit Scholarship in B.S. by the Devi Ahilya University, Indore, India
1989-93 University Grants Commission-Council of Science and Industrial Research (UGC-CSIR) and Lecturer Eligibility Fellowship, India
1992 MPSCT YOUNG SCIENTIST, Merit certificate in 7th Young Scientist conference organized by MP Council of Science and Technology, India
1992 Travel Award from CSIR, India to attend Annual Meeting of Federation of American Societies for Experimental Biology, Anaheim, California
2004 Travel Award from Retrovirology and Opportunistic Infections Society to attend the 11th conference on Retroviruses and Opportunistic Infections to be held in San Francisco from February 8-11, 2004

 

Selected Peer-reviewed Publications

Publications:

  • Verma S., Kumar G.P, Laloraya M, Singh A, Nivsarkar M and Bharti S. (1990) Discovery of a novel and alternate hydrogen peroxide generating machinery in mammalian thyroid gland that modulates iodination of tyrsine. Biochem.; Biophys. Res Commun. 169:1-7.
  • Verma S., Kumar G.P, Laloraya M, and Singh A (1990) Activation of iodine into a free radical intermediate by superoxide: A physiologically significant step in the iodination of tyrosine. Biochem.; Biophys. Res Commun. 170:1026-1034.
  • Kumar G.P, Tillo N, Laloraya M, Verma S., and Singh A (1990) Superoxide radical induces lipid phase transitions that mimics temperature induced phase transition phenomenon of membrane lipids. Biochem. Biophys. Res Commun. 172:601-606.
  • Kumar G.P, Sherwani N, Laloraya M, Verma S., and Singh A (1990) Superoxide dismutase as a regulatory switch in mammalian testicular steroidogenesis. Biochem. Biophys. Res Commun. 173:302-308.
  • Verma S ., Kumar G.P, Laloraya M, Singh A, Nivsarkar M (1991) Superoxide dismutase activation in thyroid and suppression in adrenals: a novel pituitary regulatory routes. FEBS LETTS. 282: 310-312.
  • Singh A, Kumar G.P, Laloraya M, Verma S, and Nivsarkar M (1991) Modulation of superoxide dismutase activity by spermine: its contexual significance in sperm maturation. Biochem. Biophys.Res.Commun.177:420-426.
  • Mahopatra B, Verma S, Shankar S and Suri A. (1998) Molecular cloning of human testis mRNA specifically expressed in haploid germ cells, having structural homology with the A-kinase Anchoring proteins. Biochem.; Biophys. Res Commun. 244: 540-545.
  • Verma S, Mohapatra B, Jagadish N, Selvi R, Roy P, Rana R, Lakshmi K, Suri A (2004) Molecular cloning, expression of testicular transcript abundant in germ cells and immunobiological effects of the recombinant protein. Am Jour. Reproduc. Immunol. 52 (2): 164-73.
  • S. Shankar, S. Verma, R. Selvi, N. Jagadish and A. Suri.Isolation and Characterization of a Haploid Germ Cell Specific Sperm Associated Antigen 9 (SPAG9) from the Baboon. Mol. Reprod. Develop. (in Press).
  • Verma S., Ziegler K., Bui T., Frisque RJ, Yanagihara R and Nerurkar VR (2004) Altered Patterns of Cellular Gene Expression in Primary Human Glial Cells Transfected with JC virus: Stat-1 and IFN-responsive Genes as Major Targets (communicated).
Abstracts:

  • Verma S., Kumar G.P, Laloraya M (1994); Superoxide radical as a growth modulator in thyroid. 17th Annual conference of American Society for Biochem. and Mol. Biol., Delhi.
  • Verma S. (1992) SOD and Peroxidase: components in adrenal progesterone synthesising multienzyme complex. Annual meeting of Federation of American Societies for Experimental Biology (FASEB) in Anaheim, California, USA.
  • Verma S. (1992) A re-examination of proposed inactivation of thyroglobulin by propylthiouracil. 7th MPCST Young Scientist Conference in Indore, India.
  • Verma S., Kumar G.P, Laloraya M, Singh A, Nivsarkar M and Bharti S. (1991) A possible role of superoxide radical and SOD in enzyme iodination. 31st Annual meeting of American Society of cell Biology at Boston, USA.
  • Verma S., T Bui, R J Frisque, R. Yanagihara, and Nerurkar V R (2003) Pathogenesis of progressive multifocal leukoencephalopathy (PML): Global modulation of host gene expression. In 11 th conference on Retroviruses and Opportunistic Infections held in San Francisco from Feb., 2004.
  • S Verma, K Ziegler, R J Frisque, R. Yanagihara, and V R Nerurkar (2004) Altered Patterns of Cellular Gene Expression in Primary Human Glial Cells Transfected with JC virus. In the annual conference of American Society of Virology held in Montreal, Canada from July 9 th to 14 th.

Research Funds (Active) Duration

Clinical Research Center of Hawaii
P20 RR 11091 (PI: Easa)
NIH/NCRR

 

01/01/04-12/31/04