Qigui Yu

Junior Researcher

 

Retrovirology Research Laboratory

Leahi Hospital, Atherton Building, Second Floor

3675 Kilauea Avenue, Honolulu, Hawaii 96816

TEL (808) 732-7702

FAX (808)735-3682

email: yu@pbrc.hawaii.edu

Education/Training
INSTITUTION AND LOCATION  DEGREE YEAR(s) FIELD OF STUDY
Wuannan Medical School, Wuhu, P. R. China M.D. 1981-1986 Medicine
Fourth Military Medical University, Xian, Shaanxi, P.R.China M.S. 1986-1989 Microbiology and Immunology
Fourth Military Medical University, Xian, Shaanxi, P.R.China Ph.D. 1991-1995 Molecular Virology and Immunology

Professional History
11/1997--present Junior Researcher, Retrovirology Research laboratory, Pacific Biomedical Research Center, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
09/1995--11/1997 Lecturer and Junior Researcher, Department of Etiology, Fourth Military Medical University, Xian, P. R. China
05/1996--10/1996  Visiting Scientist, Department of Tropical Medicine, University of Hawaii, Honolulu, Hawaii, USA
07/1986--09/1991 Teaching and Research Assistant, Department of Microbiology, Fourth Military Medical University, Xian, P. R. China.
07/1985--09/1986 Intern, Wuhu Secondary People's Hospital, Wannan Medical School, Wuhu, Anhui, P.R.China

Published Abstracts and Papers

  1. Yu Q, Lu Y, Nerurkar VR, and Yanagihara R. Genomic walking for the entire DNA polymerase gene of a novel herpesvirus from a green turtle with fibropapilloma. Abstracts of the 19th annual meeting of the American Society for Virology. Fort Collins, Colorado, July 14-18, 2000
  2. Yu Q, Lu Y, Nerurkar VR, and Yanagihara R. Rapid acquisition of the entire DNA polymerase gene of a novel herpesvirus from green turtle fibropapilloma by a genetic walking technique. Journal of Virological Methods 2000 (In Press).
  3. Nerurkar VR, Yu Q, Tongson J, and Yanagihara R. A genetically distinct variant of TT virus from Solomon Islands. Abstracts of the 19th annual meeting of the American Society for Virology. Fort Collins, Colorado, July 14-18, 2000
  4. Yu Q, Lu Y, Nerurkar VR, and Yanagihara R. Sequencing and analysis of DNA flanking known sequence of a novel herpesvirus from green turtle fibropapillomatosis. Archives of Virology 2000;145:1-8
  5. Lu Y, Yu Q, Zamzow JP, Wang Y, Losey GS, Balazs GH, Nerurkar VR, and Yanagihara R. Detection of green turtle herpesviral sequence in saddleback wrasse (Thalassoma duperrey): Possible mode of transmission of green turtle fibropapilloma. Journal of Aquatic Animal Health 2000;12: 58-63.
  6. Yu Q, Lu Y, Nerurkar VR, and R. Yanagihara. Studies on the turtle tumor susceptibility gene, TSG101: Full-length cDNA sequence, genomic structure analysis and role in green turtle fibropapilloma. Journal of Aquatic Animal Health 2000 (in press).
  7. Lu Y. Wang Y, Yu Q, Fink S, Aguirre AA, Balazs GH, Nerurkar VR, and Yanagihara R. Polymerase chain reaction detection of green turtle herpesviral sequence in tissues and organs of green turtle with or without fibropapilloma. Archives of Virology 2000;145:1885-1893.
  8. Chua PK, Nerurkar VR, Yu Q, Woodward CL, Melish ME, and Yanagihara R. No etiological association between Kawasaki syndrome and parvovirus B19, human herpesvirus 8 (HHV 8), TT virus (TTV), GB virus-C/hepatitis G virus (GBV-C/HGV) or Chlamydia pneumoniae. Pediatric Infectious Disease Journal 2000;19: 477-479.
  9. Lu Y, Aguirre AA, Hamm C, Wang Y, Yu Q, Loh PC, and Yanagihara R. Estanblishment, cryopreservation, and growth of 11 cell lines prepared from a juvenile Hawaiian monk seal, Monachus Schauinslandi. Methods in Cell Science 2000; 00: 1-10.
  10. Yu Q, Lu Y , Nerurkar VR, and Yanagihara R. Ligation PCR: a simple technique to amplify DNA flanking known sequences. Abstracts of the 18th annual meeting of the American Society for Virology. Amherst, Massachusetts, July 10-14, 1999 (P26-9), p.182.
  11. Chua, PK, Yu, Q, Nerurkar VR, Yamamoto KS, Melish ME, and Yanagihara R. Elevated matrix metalloproteinase 9 (MMP-9) activity in Kawasaki syndrome. Abstract of the American Pediatric Academic Societies’ 1999 Annual Meeting. San Francisco, Canifornia, May 1-4, 1999. Pedeatric Research 1999;45:195A(928)
  12. Lu Y, Yu Q, Aguirre AA, Work TM, Balazs GH, Nerurkar VR, and Yanagihara R. Detection of novel herpesviral sequences in cell culture derived from tumors of green turtles (Chelonia Mydas) with fibropapilloma. Abstracts of the 18th annual meeting of the American Society for Virology. Amherst, Massachusetts, July 10-14, 1999 (W46-11), p.143.
  13. Li X, Miao J, Xue C, Qin E, and Yu Q. Humoral immue response to the nucleic acid vaccine of merozoite surface protein 1 block 17 of the encoded gene fragment of Plasmodium Falciparum. Chinese Journal of Zoonoses 1999;15:21-23.
  14. Zhen R., Yu Q, Chen W, Fan R, and Xue C. Construction and sequencing recombinat plasmid of the thymidine kinase gene deletion mutation of the herpesvirus simplex type 1. Chinese Journal of Cellular and Molecular Immunology 1999;15:88-90.
  15. Chen W, Yu Q, Xue C, Zhen R, and Fan R. Construction and expression of herpes simplex virus Type 1 thymidine kinase fusion protein in E.coli. Chinese Journal of Cellular and Molecular Immunology 1999;15:91-93.
  16. Miao J, Xue C, Yu Q, and Qian E. Construction of a couple of eukaryotic expression recombinants containing the gene fragment of 42KD C-terminal region of Plasmodium Falciparum merozoite surface protein 1. Chinese Journal of Microbiology and Immunology 1998;18:186-188.
  17. Yu Q, Hu N, Xue C, Chen W, Fan R. Amplificattion , cloning, and sequencing of the thymidine kinase gene of herpesvirus simplex virus 1. Journal of Fourth Military medical University 1998;19:257-260.
  18. Chen W, Yu Q, Fan R, Zhen R, and Xue C. Stable long-term transfected human hepatocellular carcinoma cell line bearing HSV-1 thymidine kinase gene by retroviral vector. Chinese Journal of Cellular and Molecular Immunology 1998;14:26-28.
  19. Miao J, Xue C, Yu Q, and Qin E. Construction of a Plasmodium Falciparum merozoite surface protein 1 C-terminal region based hybrid nucleic acid vaccines and its immunogenicity. Chinese Journal of Parasitology and Parasitic Diseases 1997;15:321-325.
  20. Miao J, Xue C, Yu Q, and Qin E. Construction of hybrid nucleic acid vaccines based on Plasmodium Falciparum merozoite surface protein 1 block 17 region. WHO/TDR (world health Organization/ Training in Tropical Diseases) Workshop on Vaccine and Diagbostics for Malaria and Schistosomiasis. 1997. pp12. Guangzhou, P.R.China.
  21. Miao J, Xue C, Yu Q, Wang X, and Qin E. Immunogenicity of P. falciparum MSP-1 C-terminal region based DNA vaccines in BALB/C mice. Abstract of 10th. International Congress of Protozoology. The University of Sydney, Sydney, Australia. July 21-25, 1997.
  22. Yu Q, Qin K, Liu J, and Jiang J. Cloning and sequencing the VH and VL genes from 1A12/4D5 monoclonal antibody against HSV using PCR method. Chinese Journal of Immunology 1995;11: 202-206.
  23. Yu Q, Qin K, Liu J, and Jiang S and Wang M. Expression of single- domain antibody against HSV gC in insect cells using baculovirus as a vector. Chinese Journal of Microbiology and Immunology 1995;15:153-157.
  24. Yu Q, Liu J, Qin K, Wang M, and Jiang S. Detection and genotyping of simplex herpes simplex virus by antigen capture polymerase chain reaction (AC-PCR). Chinese Journal of Virology 1995;11:78-82.
  25. Yu Q, Qin K, Liu J, Wang M, and Jiang S. Cloning and sequencing the variable gene from the heavy chain of monoclonal antibody against HSV glycoprotein C. Chinese Journal of Microbiology and Immunology 1994;14: 226-229.
  26. Yu Q, Qin K, Liu J, Wang M, and Jiang S. Cloning and sequencing of the VL gene from cDNA library of monoclonal antibody 1A12 against HSV glycoprotein C. Chinese Journal of Monoclonal Antibody 1994;10:14-17.
  27. Xu T, Yu Q, Liu L, and Zhu Z. A Study on the use of SM44 strain and 17 Syn+ strain herpes simplex virus type 1 as transneuronal tracers. Chinese Journal of Neuroanatomy 1994;10:197-201.
  28. Qin K, Yu Q, Jiang S, and Wang M. Idetification and characterization of a 30K glycoprotein of HSV-2. Journal of General Virology 1992; 73: 1693-1701.
    29.
  29. Qin K, Yu Q, Jiang S, and Wang M. HSV infection in China. Virus Information Exchange Newsletter 1992; 9: 13.
  30. Zhu Q, Lin L, Qin K, Yu Q, Wang M. HSV infection and associated diseases in Taiyuan. Virus Information Exchange Newsletter 1992;9:13.
  31. Zhu Q, Lin L, Qin K, Yu Q, Wang M. Detecting and typing Herpes simplex virus antigen in CSF by McAb-ELISA. Virus Information Exchange Newsletter 1992;9:14.
  32. Yu Q, Qin K, Gao Q, Jiang S, and Wang M. Identification and gene location of target antigens of anti-HSV monoclonal antibodies. Chinese Journal of Microbiology and Immunology 1991;11: 212-215.
  33. Yu Q, Qin K, Wang M, Jiang S, Li L, Zhu Q, and Zhao R. Study for detecting herpesvirus simplex virus type-specific antigen in swabs from genital herpes using enzyme-linked immunosorbent assay. Chinese Journal of Monoclonal Antibody 1991;7:49-53.
  34. Qin K, Yu Q, Yang L, Wang M, and Jiang S. Characterization of herpes simplex virus glycoproteins and clinical application of monoclonal antibodies to herpesvirus simplex virus. Chinese Journal of Monoclonal Antibody 1991;7:31-35.
  35. Yu Q, Qin K, Gao Q, Jiang S, and Wang M. Identification of glycoprotein C of Herpes simplex virus using radioimmunoprecipitation (RIP) assay. Chinese Journal of Immunology 1990;6: 333-337.

Manuscripts in Preparation

  1. Yu Q, Nerurkar VR, Shiramuzu B, Hu N, Shikuma CM, Melish ME, Cascio K, Imrie A, Lu Y, and Yanagihara R. TT virus: preferential distribution in CD19+ peripheral blood mononuclear cells and lack of viral integration 
  2. Yu Q, Nerurkar VR, Hu N, Tongson J, Yanagihara R. A genetically distinct variant of TT virus from Solomon Islands.
  3. Yu Q, Nerurkar VR, Hu N, and Yanagihara R. TT virus prevalence in plasma, PBMC, and urine of patients with Kawasaki syndrome.
  4. Yu Q, Chua PK, Nerurkar VR, Yamamoto KS, Melish ME, and Yanagihara R. Overexpression of matrix metalloproteinase 9 (MMP-9) with elevated activity by PBMC in Kawasaki syndrome.
  5. Yu Q, Shiramizu B, Nerurkar VR, Hu N, and Yanagihara R. Non-neuroinvasion of TT virus in children with acute leukemia or Kawasaki syndrome.