Lingbing Zeng  

Junior Researcher

Retrovirology Research Laboratory

Atherton Building, Leahi Hospital, Second Floor

3675 Kilauea Avenue, Honolulu, Hawaii 96816

TEL (808) 732-7702

FAX (808)735-7544

email: lingbing@hawaii.edu

   

 

INSTITUTION AND LOCATION DEGREE YEAR(s) FIELD OF STUDY
Wuhan University, Wuhan, China B.S. 1983 Virology
Hauzhong University of Science & Technology, Wuhan, China M.S. 1999

Biomedicine Engineering
Wuhan Univeristy, Wuhan, China Ph.D. 2002  
University of Hawaii, USA   2005 Medical Molecular Virology
 
Professional Experience
1983-2001 Technology for Controlling Grass Carp Hemorrhage Virus: Virus isolation classification and cultivation in Grass carp kidney cells; Cell cultured killed vaccine production in large-scale for practical application; Immunological response of Grass carp to the immunization with killed vaccine (Yangtze River Fisheries Research Institute, P.R. China)
2002-2005

Development of Gene Transfer Approaches to NeuroAIDS: HIV-1-based defective lentiviral vector-mediated gene transfer in human monocytes/macrophages and uppression of wild-type HIV-1-replicaiton. (RRL, PBRC, University of Hawaii at Manoa, USA)

 

Honors and Awards

1985 Establishment of cell line derived from Grass carp kidney and isolation of grass carp hemorrhage virus. 2nd grade award of the science and technology advancement, the ministry of agriculture of China. Major participator.
1990 Cell cultured killed vaccine against the Grass carp hemorrhage virus. 1st grade award of the science and technology advancement, Chinese academy of fishery science. Ranked 5th.
1991 The prevention and treatment techniques against the Grass carp hemorrhage. 1st grade award of the science and technology advancement, the ministry of agriculture of China. Ranked 13th.
1993 The prevention and treatment techniques against the Grass carp hemorrhage. 1st grade award of national science and technology advancement. Ranked 13th.
1996 Rearing two species of farmed Grass carp with anti-degeneration characters. 2nd grade award of the science and technology advancement, Chinese academy of fishery sciences. Ranked 6th.
2002 Technology for large-scale production of cell cultured killed vaccine against the Grass carp hemorrhage virus. 3rd grade award of the science and technology advancement. Hubei province. Chair of the project.

Publications

  • Lingbing Zeng, Yuanan Lu, et al. 2005. HIV-1-based lentiviral vectors efficiently transduce human monocyte-derived macrophages and suppress replication of wild-type HIV-1. The Journal of Gene Medicine (Accepted).

  • Lingbing Zeng, Yuanan Lu, et al. 2005. Highly effective gene transfer in primary mouse blood and bone marrow-derived monocytes /macrophages achieved with defective HIV-1-based lentiviral vector. Journal of Medical Virology (Submitted).

  • Lingbing Zeng, Yuanan Lu, et al. 2005. Efficient gene transfer with HIV-1-based defective lentiviral vectors in various cell lines in vitro. Virus Research (in preparation).

  • Yuanan Lu, Lingbing Zeng et al. Characterization of HIV-1-derived vector-mediated gene transduction of primary culture of monocyte-derived macrophages in vitro. 24 th Annual Meeting of American Society for Virology. June 18-22, 2005 Pennsylvania State Univ. (Presentation).

  • Yuanan Lu, Chunyong Liu, Lingbing Zeng, et al. 2004. Efficient gene transfer into human monocytes-derived macrophages using defective lentivirus. Cellular and Molecular Biology. Vol 49:1151-1156.

  • Guitang Wang, Scott LaPatra, Lingbing Zeng, et al. 2004. Establishment, growth, cryopreservation and species of origin identification of three cell lines from white sturgeon, Acipenser transmontanus. Methods in Cell Sciences. Vol 25: 211-220.

  • Yuanan Lu, A. Alonso Aguirre, Yun Wang, Lingbing Zeng, et al. 2003. Viral susceptibility of newly established cell lines from the Hawaiian monk seal Monachus schauinslandi. Diseases of Aquatic Organisms. Vol 57: 183-191.

  • Lingbing Zeng, et al. 1998. Technology for large-scale production of cell cultured killed vaccine against the Grass carp hemorrhage. Fishery Sciences of China. Vol 5: 62-67.

  • Lingbing Zeng, et al. 1998. The physi-chemical, biological and genomic characteristics of Grass carp hemorrhage virus strain 854. Journal of fisheries of China. Vol 22: 279-282.

  • Lingbing Zeng, et al. 1991. SDS-PAGE analysis of genome of Grass carp hemorrhage virus strain 854 and its nucleic acid type. Freshwater fisheries. Vol 21: 17-19.