Researcher, Békésy Laboratory of Neurobiology (PBRC)
Director, Békésy Laboratory of Neurobiology
Area 1: Evolution of Myelin
In a collaboration with Petra Lenz (PBRC) and Ann Castelfranco (PBRC) we are making an integrated study of myelin evolution with a focus on invertebrates. Research on this innovation involves integration of many biological levels, linking studies of:
Viewed in the broad context of innovation, myelin may provide a useful tool for studies in evolutionary biology.
Area 2: Neuroecology of Zooplankton Sensory and Motor Systems (in collaboration with Dr. Petra Lenz and others)
In this work, we are examining the relation between physiological and morphological properties of the sensory and motor systems of crustaceans, comparing pelagic and planktonic forms with benthic groups. We are interested in the evolution and ecology of these systems. Both systems reflect unusual adaptations to pelagic life when compared to similar systems in benthic and nektonic forms. Particular modifications of these sensory properties may reflect differences in ecology among phyletic groups. Of particular recent interest have been mechanisms involved in predator-evasion behavior in calanoid copepods including:
Selected (for a more complete list, see personal web pages):
Area 1: Crustacean myelin and myelin evolution
Wilson, C.H. and Hartline, D.K. (2011) The novel organization and development of copepod myelin. I. Ontogeny J. Comp. Neurol. 519:3259-3280.
Wilson C.H. and Hartline D.K. (2011) The novel organization and development of copepod myelin. II. Non-glial origin. J. Comp. Neurol. 519:3281-3305.
Hartline, D.K. (2008) "What is myelin?" Neuron Glia Biol. 4(2): 153-163
Hartline, D.K. and Colman, D.R. (2007) "Rapid conduction and the evolution of giant axons and myelinated fibers." Curr. Biol. 17: R29-R35.
Area 2: Copepod neuroecology
Burdick, D.S., Hartline, D.K. and Lenz P.H. (2007). Escape strategies in co-occurring calanoid copepods. Limnol. Oceanogr. 52: 2373-2385.
Hartline, D.K. (2011) The evolutionary origins of glia. Glia 59:1215-1236.
Hartline D.K. and Christie A.E. (2010) Immunohistochemical mapping of histamine, dopamine, and serotonin in the central nervous system of the copepod Calanus finmarchicus (Crustacea; Maxillopoda; Copepoda). Cell Tissue Res. 341(1):49-71
Castelfranco, A.M. and Hartline, D.K. (2004) Corrections for space-clamp errors in measured parameters of voltage-dependent conductances in a cylindrical neurite Biol. Cybern. 90: 280-290. [PDF]