Eötvös Loránd University, Ph.D. (Biochemistry)

Eötvös Loránd University M.S. (Chemistry)

The main aim of my research interest is to investigate the macromolecular structures and processes underlying contractility and motility of muscle and animal cells. This interest includes a wide range of topics in biochemistry, structural biology, and fluorescence spectroscopy, such as the analysis of structure-function relationships, biomolecular interactions, and protein folding. I have also worked on computational modeling of the three-dimensional structures of different proteins involved in a variety of physiologically and pathologically important functions, specifically the dynein ATPase motor proteins of the AAA+ superfamily, rhodanese-like sulfotransferases, the TRPM7 ion channel, hantavirus nucleocapsid proteins, and GDE1, a novel mammalian glycerophosphoinositol phosphodiesterase. This line of research currently bears on docking simulations of newfound interactions between ornithine decarboxylase and sepiapterin reductase that regulate oncogenicity in neuroblastoma. In my continued commitment to biochemistry, I serve as the Editor-in-Chief of Biochemistry Insights. Visit the journal’s web page.

Mocz G, Ross J. Fluorescence techniques in analysis of protein-ligand interactions. In: Protein-ligand interactions. Eds. Daviter T, Williams M, 2013, Humana Press, Springer Science+Business Media

Thangadurai D, Hall SG, Manimekalan A, Mocz G. Fisheries, aquaculture and biotechnology. 2009 Agrobios (India), Jodhpur, doi: ISBN-13: 978-81-7754-381-0.

Kang HJ, Bennett SN, Sumibcay L, Arai S, Hope AG, Mocz G, Song JW, Cook JA, Yanagihara R. Evolutionary insights from a genetically divergent hantavirus harbored by the European common mole (Talpa europaea). PLoS One. 2009 Jul 7;4(7):e6149.

Hermosura MC, Cui AM, Go RC, Davenport B, Shetler CM, Heizer JW, Schmitz C, Mocz G, Garruto RM, Perraud AL. Altered functional properties of a TRPM2 variant  in Guamanian ALS and PD. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18029-34.

Arai S, Ohdachi SD, Asakawa M, Kang HJ, Mocz G, Arikawa J, Okabe N, Yanagihara R. Molecular phylogeny of a newfound hantavirus in the Japanese shrew mole (Urotrichus talpoides). Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16296-301.